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doi: 10.1038/nrendo.2018.18 3 HuXChenYShenYTianRShengYQueH

Additionally, recent clinical evidence has demonstrated that newly diagnosed hypothyroid individuals exhibit elevated malondialdehyde (MDA) and decreased total antioxidant capacity, supporting the link between impaired antioxidant status and heightened oxidative stress (Sultana et al

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To mitigate IGF-1 side effects such as joint pain, swelling, and nerve compression, bodybuilders can follow several strategies: use the lowest effective dose under medical supervision, rotate injection sites, maintain proper hydration, support joints with supplements like glucosamine or omega-3 fatty acids, and incorporate stretching and mobility exercises